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Cryptomeria japonica D. Don - Japanese cedar

A very rare essential oil is extracted from the aromatic wood and the needles of Japanese cedar . "Sickle" because the constantly falling branches are shaped like primitive sickles and also because the needles of Japanese giant tree are curved like a sickle.

I have found some studies on the mode of action of the two essential oils:

• on mice with prostate cancer Turned out that a newly found Abietan-diterpene with the scientific name of 6-hydroxy-5 ,6-dehydrosugiol (HDHS) a significant androgen-receptor antagonist. With once-daily 0.5 and 2.5 mg / kg (in mice), 24 used the essential oil long suppressed tumor growth by 22% and 39%, was also apoptosis (programmed cell death) of the diseased cells accelerated. Lin FM, Tsai CH, Yang YC, Tu WC, Chen LR, Liang YS, Wang SY, Shyur LF, Chien SC, Cha TL, Hsiao PW. A novel diterpene suppresses tumor growth in vivo CWR22Rv1 through antiproliferation and proapoptosis. Cancer Res 2008 Aug 15; 68 (16) :6634-42.
• Various plant parts of Cryptomeria were studied in the laboratory for their insektifuge (insect driving) effect on mosquitoes (Aedes aegypti and Aedes albopictus ), the extract of the needles was the most effective, this in turn the main ingredient terpineol-4 (also reichtlich occurring in tea tree oil). Gu HJ, Cheng SS, Lin CY, Huang CG, Chen WJ, Chang ST. Repellency of essential oils of Cryptomeria japonica (Pinaceae) against adults of the mosquitoes Aedes aegypti and Aedes albopictus (Diptera: Culicidae).
  J Agric Food Chem 2009 Dec 9; 57 (23) :11127-33.
  
• The essential oil from the needles of Cryptomeria showed good activity against antibiotic-resistant bacteria such as Propionibacterium acnes and Staphylococcus epidermidis, which occur in acne. Yoon WJ, Kim SS, Oh TH, Lee NH, Hyun CG. Cryptomeria japonica essential oil inhibits the growth of drug-resistant skin pathogens and LPS-induced nitric oxide and pro-inflammatory cytokine production. Pol J Microbiol. 2009, 58 (1) :61-8.

this particular essential oil is available for example at Maienfels . Who wants to see Ruth sitting of Brunswick in the largest cedars of Ireland, look here .